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ZSCAN5D Gene

protein-coding   GIFtS: 23

GC19P056751
zinc finger and SCAN domain containing 5D
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for ZSCAN5D gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases & Descriptions
zinc finger and SCAN domain containing 5D1 2
ZNF495D1 2
putative zinc finger and SCAN domain-containing protein 5D2

External Ids:    HGNC: 377061   Entrez Gene: 6466982   Ensembl: ENSG000002128397   UniProtKB: P0CG003   

Export aliases for ZSCAN5D gene to outside databases


Summaries
for ZSCAN5D gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: ZSA5D_HUMAN, P0CG00
Function: May be involved in transcriptional regulation (By similarity)


Genomic Views
for ZSCAN5D gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 60), Regulatory elements and Epigenetics data according to Qiagen and/or SABiosciences)
About This Section
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ZSCAN5D
         Other transcription factors

   Search SABiosciences Chromatin IP Primers for ZSCAN5D

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays 


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.43   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.43

ZSCAN5D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZSCAN5D gene location

GeneLoc gene densities for chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P056751:  view genomic region     (about GC identifiers)

Start:
 56,751,773 bp from pter
End:
 56,758,866 bp from pter
Size:
 7,094 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  

Proteins
for ZSCAN5D gene

(According to 1UniProtKB, neXtProt, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, and/or ProSpec,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Dec 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, and/or Epitomics)
About This Section
UniProtKB/Swiss-Prot: ZSA5D_HUMAN, P0CG00 (See protein sequence)
Recommended Name: Putative zinc finger and SCAN domain-containing protein 5D  
Size: 497 amino acids; 56244 Da
Subcellular location: Nucleus (By similarity)
Caution: Could be the product of a pseudogene

Explore the universe of human proteins at neXtProt for ZSCAN5D: NX_P0CG00 



ENSEMBL proteins: 
ENSP00000384482 


Human Recombinant Proteins 
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2 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005622 intracellular IEA--
GO:0005634 nucleus IEA--
About this table

ZSCAN5D for ontologies           About GeneDecksing



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Protein Domains/
Families
for ZSCAN5D gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
ZSCAN5D for domains           About GeneDecksing

5 InterPro domains/families:
 IPR008916 Retrov_capsid_C
 IPR003309 Tscrpt_reg_SCAN
 IPR015880 Znf_C2H2-like
 IPR013087 Znf_C2H2/integrase_DNA-bd
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry P0CG00

ProtoNet protein and cluster: P0CG00

UniProtKB/Swiss-Prot: ZSA5D_HUMAN, P0CG00
Similarity: Contains 5 C2H2-type zinc fingers
Similarity: Contains 1 SCAN box domain


Gene Function
for ZSCAN5D gene

(According to UniProtKB, IUBMB,and/or Genatlas, Animal models from MGI Dec 24 2010,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich, microRNA from Sigma-Aldrich, Qiagen, SABiosciences, Clones from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, Cell Lines from GenScript, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: ZSA5D_HUMAN, P0CG00
Function: May be involved in transcriptional regulation (By similarity)

Inhib.
RNA:    		Browse for Gene Knock-down Tools from Millipore
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miRNA:Browse microRNA Mimics at Sigma-Aldrich
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Search SABiosciences for Assays for microRNAs that regulate ZSCAN5D

Gene
Editing:		Browse CompoZr Knockout ZFN at Sigma-Aldrich 

Clones:Browse Clones for the Expression of Recombinant Proteins Available from Millipore
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Cell
Lines:  		GenScript Custom overexpressing Cell Line Services for ZSCAN5D 

4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0003676 nucleic acid binding IEA--
GO:0003700 sequence-specific DNA binding transcription factor activity IEA--
GO:0008270 zinc ion binding IEA--
GO:0046872 metal ion binding IEA--
About this table

ZSCAN5D for ontologies           About GeneDecksing


Pathways & Interactions
for ZSCAN5D gene

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB, Sets of similar genes according to GeneDecks, PCR Arrays from SABiosciences, Proteins Network according to SABiosciences, Sigma-Aldrich, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Dec 2010 via Entrez Gene).
About This Section

    SABiosciences Custom Pathway-Focused PCR Arrays for ZSCAN5D 

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZSCAN5D

2 Gene Ontology (GO) biological process terms (GO ID links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006355 regulation of transcription, DNA-dependent IEA--
GO:0016032 viral reproduction IEA--
About this table

ZSCAN5D for ontologies           About GeneDecksing



Drugs & Compounds
for ZSCAN5D gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section
Browse Small Molecules at Sigma-Aldrich
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZSCAN5D


Transcripts
for ZSCAN5D gene

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore,
siRNAs from Sigma-Aldrich, OriGene, Qiagen, Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from Sigma-Aldrich, Qiagen, SABiosciences,
Tagged/untagged cDNA clones from OriGene, Sigma-Aldrich, GenScript, Primers from OriGene and/or SABiosciences)
About This Section
Inhib.
RNA:     		Browse for Gene Knock-down Tools from Millipore
Browse Nano Scale siRNA at Sigma-Aldrich
Sigma-Aldrich siRNA for ZSCAN5D
Browse shRNA at Sigma-Aldrich
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Browse OriGene siRNA
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miRNA: Browse microRNA Mimics at Sigma-Aldrich
Browse microRNA target validation systems at Sigma-Aldrich 
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of ZSCAN5D 
Search SABiosciences for Assays for microRNAs that regulate ZSCAN5D
Clones: Browse FLAG tag genes at Sigma-Aldrich
Browse OriGene untagged/tagged cDNA clones in CMV expression vector
Browse 3'-UTR reporter clones for miRNA target validation 
Browse OriGene MicroRNA Expression Plasmids 
GenScript Custom cDNA clone Services for ZSCAN5D 
Primers:Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs 
Search SABiosciences RT2 qPCR Primer Assays for ZSCAN5D

Additional cDNA sequence: XM_001725568.1 

Unigene Cluster for ZSCAN5D:

Zinc finger and SCAN domain containing 5D
Hs.631578
Unigene Representative Sequence: XM_001725568


GeneLoc Exon Structure

1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000391528

Expression
for ZSCAN5D gene

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 228 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Primers from OriGene and/or SABiosciences )
About This Section

ZSCAN5D expression in normal and diseased human tissues

1 Data from GNF BioGPS
    About these images

ZSCAN5D gene expression
ZSCAN5D gene electronic northern expression
ZSCAN5D gene sage expression
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.631578
Primers:Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs 
Search SABiosciences RT2 qPCR Primer Assays for ZSCAN5D
    SABiosciences Custom PCR Arrays for ZSCAN5D 


Orthologs
for ZSCAN5D gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Dec 24 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for ZSCAN5D gene from 1 species
Organism Gene Locus Description Human
Similarity		 NCBI accessions
chimpanzee
(Pan troglodytes)		 ZSCAN5A1   -- zinc finger and SCAN domain containing 5A 98.82(n)
98.23(a)		 469021  XM_524406.2  XP_524406.2 
About this table        Species with no ortholog for ZSCAN5D

ENSEMBL Gene Tree for ZSCAN5D (if available)

Paralogs
for ZSCAN5D gene

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
Paralogs for ZSCAN5D gene
ZSCAN5A2  ZSCAN5C2  ZSCAN5B2  

ZSCAN5D for paralogs           About GeneDecksing



Genomic Variants
for ZSCAN5D gene

(SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section

10/185 NCBI SNPs in ZSCAN5D are shown (see all 185)
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidChr 19 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
----------
rs10362411,2
C,F,A,H,56750672(+) ATTTGT/CGAATC 1 -- ng5114Minor allele frequency- C:0.50NA EA NS WA 704
rs10362421,2
C,F,A,H,56750675(+) TGTGAG/ATCAGT 1 -- ng5113Minor allele frequency- A:0.49MN NS EA NA WA 748
rs10362431,2
C,F,A,H,56750685(+) TCAGCA/GGATGC 1 -- ng5113Minor allele frequency- G:0.47MN NA EA WA 698
rs10362441,2
C,F,A,H,56751782(+) GGCAGT/CGCAGG 2 /R /C mis1 ref117Minor allele frequency- C:0.33EA NA MN NS 1192
rs20334851,2
C,A,H,56752354(+) attacA/Tggcgt 1 -- int15Minor allele frequency- T:0.49NA EA WA 96
rs20334861,2
C,F,O,H,56752381(+) cGCACA/TCCACT 1 -- int118Minor allele frequency- T:0.49NS EA NA WA 1322
rs20334871,2
C,F,A,56757649(+) TTTAGA/GCAGGG 1 -- int115Minor allele frequency- G:0.16NS EA NA 1098
rs20334881,2
C,F,56757661(+) AGTCAT/CTGCTG 1 -- int19Minor allele frequency- C:0.14NA EA 466
rs21169361,2
C,A,56753234(+) ATTCGG/CTGGGT 1 -- int14Minor allele frequency- C:0.46NA EA WA 94
rs21169371,2
C,F,56753316(+) AGGATG/ATGAGG 1 -- int18Minor allele frequency- A:0.11NS EA 830
About this table

HapMap Linkage Disequilibrium images for ZSCAN5D (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for ZSCAN5D: --

QIAGEN SeqTarget long-range PCR primers for resequencing ZSCAN5D 

Disorders & Mutations
for ZSCAN5D gene

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, and/or TGDB.)
About This Section
   --

Medical News
for ZSCAN5D gene

(Possibly Related Articles in Doctor's Guide)
About This Section
   --

Publications
for ZSCAN5D gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6UniProtKB/TrEMBL, and/or 7Novoseek)
About This Section

1 PubMed article for ZSCAN5D gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZSCAN5D)
  1. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)

External Searches for ZSCAN5D gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing ZSCAN5D gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 646698 HGNC: 37706 Ensembl:ENSG00000212839 euGenes: HUgn646698 ECgene: ZSCAN5D
H-InvDB: ZSCAN5D

Other Databases showing ZSCAN5D gene

(According to HUGE)
About This Section
   --

Specialized Databases showing ZSCAN5D gene

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
   --

Intellectual Property
for ZSCAN5D gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from XenneX, Inc.)
About This Section
Patent Information for ZSCAN5D gene:
Search GeneIP for patents involving ZSCAN5D

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for ZSCAN5D gene

(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or Enzo Life Sciences)
About This Section

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