Aliases &
Descriptions
for ZSWIM7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases & Descriptions |
|---|
| zinc finger, SWIM-type containing 71 2 | | SWS11 2 3 | | SWIM domain-containing and Srs2-interacting protein 1 homolog2 3 | | SWIM-domain containing Srs2 interacting protein 12 | | zinc finger SWIM domain-containing protein 72 | | SWIM domain containing Srs2 interacting protein 12 |
Export aliases for ZSWIM7 gene to outside databasesPrevious GC identifer: GC17U900830 |
Summaries
for ZSWIM7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZSWM7_HUMAN, Q19AV6Function: Involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaksarising during DNA replication or induced by DNA-damaging agents
|
Genomic Views
for ZSWIM7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 60),
Regulatory elements and Epigenetics data according to
Qiagen and/or
SABiosciences)
About This Section
|
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZSWIM7
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZSWIM7
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays for ZSWIM7  |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p12 Ensembl cytogenetic band: 17p12 HGNC cytogenetic band: 17p11.2ZSWIM7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M015820: view genomic region
(about GC identifiers)
Start:
|
15,747,186 bp from pter |
End:
|
15,770,054 bp from pter |
Size:
|
22,869 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr17- 15,879,874-15,903,031 |
RefSeq DNA sequence:- NC_000017.10 NT_010718.16
|
Proteins
for ZSWIM7 gene
(According to
1UniProtKB,
neXtProt,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological, and/or
ProSpec,
Biochemical Assays by
Millipore,
Sigma-Aldrich,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Dec 2010 and
Entrez Gene,
Antibodies by
Millipore,
Sigma-Aldrich,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals, and/or
Epitomics)
About This Section
|
UniProtKB/Swiss-Prot: ZSWM7_HUMAN, Q19AV6 (See
protein sequence)Recommended Name: Zinc finger SWIM domain-containing protein 7 Size: 140 amino acids; 15386 Da
Subunit: Interacts with RAD51L3
Subcellular location: Nucleus (Probable)Explore the universe of human proteins at neXtProt for ZSWIM7: NX_Q19AV6
REFSEQ proteins (2 alternative transcripts):
NP_001036162.1 NP_001036163.1
ENSEMBL proteins: ENSP00000382218 ENSP00000419138
Human Recombinant Proteins
1 Gene Ontology (GO) cellular component term (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
About this table
ZSWIM7 for ontologies About GeneDecksing
Antibodies for ZSWIM7:
Assays for ZSWIM7: |
Protein
Domains/
Families
for ZSWIM7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZSWIM7 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q19AV6ProtoNet protein and cluster: Q19AV6 UniProtKB/Swiss-Prot: ZSWM7_HUMAN, Q19AV6Similarity: Belongs to the SWS1 familySimilarity: Contains 1 SWIM-type zinc finger |
Gene Function
for ZSWIM7 gene
(According to UniProtKB,
IUBMB,and/or
Genatlas, Animal models from MGI Dec 24 2010,
shRNA from
OriGene,
Sigma-Aldrich,
RNAi from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Clones from Millipore,
Sigma-Aldrich,
OriGene,
GenScript,
Sino Biological,
Cell Lines from GenScript,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene.)
About This Section
|
UniProtKB/Swiss-Prot: ZSWM7_HUMAN, Q19AV6Function: Involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaksarising during DNA replication or induced by DNA-damaging agents
2 Gene Ontology (GO) molecular function terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008270 | zinc ion binding |
IEA | -- | | GO:0046872 | metal ion binding |
IEA | -- |
About this table
ZSWIM7 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZSWIM7 gene
(Pathways according to
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
PCR Arrays from
SABiosciences,
Proteins Network according to
SABiosciences,
Sigma-Aldrich,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Dec 2010 via
Entrez Gene).
About This Section
|
SABiosciences Custom Pathway-Focused PCR Arrays for ZSWIM7
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZSWIM7
2 Gene Ontology (GO) biological process terms (GO ID links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006281 | DNA repair |
IEA | -- | | GO:0006310 | DNA recombination |
IEA | -- |
About this table
ZSWIM7 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZSWIM7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for ZSWIM7
|
Transcripts
for ZSWIM7 gene(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 228 Homo sapiens; Dec 8 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
Millipore,
siRNAs from
Sigma-Aldrich,
OriGene,
Qiagen,
Super-pooled esiRNAs from Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
microRNA from Sigma-Aldrich,
Qiagen,
SABiosciences,
Tagged/untagged cDNA clones from
OriGene,
Sigma-Aldrich,
GenScript,
Primers from
OriGene and/or
SABiosciences)
About This Section
|
REFSEQ mRNAs for ZSWIM7 gene (2 alternative transcripts): NM_001042697.1 NM_001042698.1 Additional cDNA sequence: AK093384.1 BC018807.1 BC044842.1 BC066344.1 BC089386.1 BC094855.1 CR593112.1 DQ530600.1 13 DOTS entries: DT.87015989 DT.101959939 DT.100817644 DT.120903608 DT.100817645 DT.100027091 DT.97765299 DT.120903406 DT.100799567 DT.100027092 DT.120903478 DT.40121212 DT.100701898 Unigene Cluster for ZSWIM7: Zinc finger, SWIM-type containing 7 Hs.593985 [show with all ESTs]Unigene Representative Sequence: NM_001042697
GeneLoc Exon Structure
15 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000399277(uc002gpe.2 uc002gpf.2 uc002gpg.2) ENST00000460252
ENST00000486706 ENST00000497434 ENST00000476496 ENST00000486655 ENST00000475498
ENST00000399280 ENST00000472495 ENST00000497719 ENST00000474716 ENST00000491631
ENST00000495825 ENST00000460315 ENST00000490395
|
Expression
for ZSWIM7 gene
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 228 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Primers from
OriGene and/or
SABiosciences
)
About This Section
| ZSWIM7 expression in normal and diseased human tissues
1 / 2 6 probe-sets matching ZSWIM7 gene
Affymetrix
probe-set |
Array |
GeneAnnot data |
GeneNote data |
GeneTide data |
| # genes |
Sensitivity |
Specificity |
Correlation |
Length |
Gb_Accession |
Consensus |
Uniqueness |
Score |
Rank |
| 49390_at2
|
U95-B |
1 |
1.00 |
1.00 |
0.34 |
1.05 |
-- |
-- |
-- |
-- |
-- |
| 49393_at2
|
U95-B |
1 |
0.94 |
1.00 |
0.66 |
0.95 |
-- |
-- |
-- |
-- |
-- |
| 229119_s_at2
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 228719_at2
|
U133-B |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 229119_s_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
| 228719_at2
|
U133Plus2 |
1 |
1.00 |
1.00 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
About this table
ZSWIM7 for expression About GeneDecksing
Data from
Genenote
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: TTGTGTCCAC
SOURCE GeneReport for Unigene cluster: Hs.593985
SABiosciences Custom PCR Arrays for ZSWIM7
|
Orthologs
for ZSWIM7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Dec 24 2010,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for ZSWIM7 gene from 5 species
About this table Species with no ortholog for ZSWIM7
ENSEMBL Gene Tree for ZSWIM7 (if available) |
Paralogs
for ZSWIM7 gene(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
Genomic Variants
for ZSWIM7 gene(SNPs according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Resequencing Primers from Qiagen)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Chr 17 pos | Sequence | Recs | AA
Chg | Type | More | Recs | Allele
freq | Pop | Total
sample | More |
|---|
About this tableHapMap Linkage Disequilibrium images for ZSWIM7 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZSWIM7
1 CNV: 67148
1 Indel: 25784 | | QIAGEN SeqTarget long-range PCR primers for resequencing ZSWIM7 |
|
Disorders & Mutations
for ZSWIM7 gene
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
LSDB, HGMD, GAD,
HuGE Navigator,
and/or TGDB.)
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| -- |
Medical News
for ZSWIM7 gene(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for ZSWIM7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6UniProtKB/TrEMBL, and/or
7Novoseek)
About This Section
|
3 PubMed articles for ZSWIM7 gene integrated from 7 sources:
(articles sorted by number of sources associating them with ZSWIM7)- Sws1 is a conserved regulator of homologous recombination in eukaryotic cells. (PubMed id 16710300)1, 2, 3 Martin V.... Russell P. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZSWIM7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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|
|
Genome Databases showing ZSWIM7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZSWIM7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZSWIM7 gene(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZSWIM7 gene:
Search GeneIP for patents involving ZSWIM7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZSWIM7 gene(Antibodies, recombinant proteins, and assays by Millipore, Sigma-Aldrich, R&D Systems, Qiagen, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Epitomics, ProSpec, Uscn,
Clones available from Millipore, Sigma-Aldrich, OriGene, GenScript, Sino Biological, PCR Arrays from SABiosciences, Drugs and/or compounds by Sigma-Aldrich, Tocris Bioscience, and/or
Enzo Life Sciences)
About This Section
|
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| |  | Search Tocris compounds for ZSWIM7 |
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